Double-Blind Placebo-Controlled Randomised Clinical Trials General forum
1 replies. Last post: 2020-07-23
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1 replies. Last post: 2020-07-23
Reply to this topic Return to forumCould you get the same results if each partial treatment is random
Examples:-
Current trial 50% receive the drug for 10 treatments and 50% get 10 placebos
Compared with a trail where each treatment is random, if 10 treatments then 1 in 1024 chance of receiving drug each time,
same chance to get placebo, the rest as in a binomial distribution
The idea been if a drug is worth testing then limit the chance of zero and 100% use happening
This was triggered by Dr John Campbell stating when he was applying a trail he knew that the patient was on placebo because no reaction
and likely to die